Enhanced Hemostatic and Antibacterial Biomedical Hydrogel Utilizing Bio-Extracts for Advanced Wound Management
Keywords:
Biomedical hydrogel, Sericin, Tannin extract, Banana trunk juiceAbstract
Minor wounds are susceptible to bacterial infection when left untreated, potentially leading to serious complications. This study develops an innovative biomedical hydrogel using sericin extracted from silk degumming waste, combined with tannin extracts derived from Indian almond (Terminalia catappa) leaves, and further enhanced with banana trunk juice (Musa paradisiaca) for improved blood coagulation. Tannins provide potent antibacterial properties, while bioactive compounds in banana trunk juice promote platelet aggregation and clotting. The hydrogel was comprehensively evaluated for antibacterial activity against Staphylococcus aureus and Escherichia coli, swelling capacity, mechanical flexibility, degradation rate, gel fraction, and coagulation efficiency. Results demonstrate that the incorporation of these natural bio-extracts significantly improves both antimicrobial and hemostatic properties. The developed hydrogel shows promise as an eco-friendly, cost-effective wound dressing material that repurposes agricultural and industrial waste streams.
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